HBSAG FREE GAMMA GLOBLIN MANUFACTURE AND PRODUCT

摘要

Methods for producing from human serum, human gamma globulin essentially free of HBsAg and products resulting therefrom. Specifically provided are ion exchange resin/buffer systems capable of effectively removing HBsAg thought to be closely correlated with viral hepatitis type B infectivity. Additional steps can include ultrafiltration to increase reduction of any virus not removed in the column passage as well as the addition of anti-HBg to substantially eliminate all infectivity.