Quinoline derivatives, process for their preparation and pharmaceutical compositions containing them.

摘要

<CHEM> in which R<1> to R<4> are the same or different and are inter alia, each hydrogen, C1-4alkyl, C1-6alkoxy, phenyl, C1-6alkylthio, C1-4alkanoyl, amino, R<5> to R<9> are the same or different and are each hydrogen, C1-6alkyl, C1-6alkoxy, C1-6alkylthio, halogen, cyano, amino, hydroxy, carbamoyl, carboxy, C1-6alkanoyl, trifluoromethyl or nitro, R<1><0> is inter alia hydrogen, C1-6alkyl, C1-6alkoxy, halogen, hydroxy, -CH2OH, C1-6alkylthio, NH(CH2)nOH in which n is 0 to 4 or amino; and A is -(CH2)2-, (CH2)3- or -CH=CH-; processes for their preparation, pharmaceutical compositions containing them and their use in therapy as inhibitors of gastric acid secretion.