FREMGANGSMAATE FOR RENSING AV UREN ALFA-L-ASPARTYL-L-FENYLALANINMETHYLESTER (ALFA-APM).

摘要

A method for separating alpha -L-aspartyl-L-phenylalanine methyl ester ( alpha -APM) from a solution containing alpha -APM and impurities associated with the production thereof which comprises adding a mineral acid or an organic sulfonic acid to the solution in an organic carboxylic acid or in a solvent containing an organic carboxylic acid, and isolating the pure salt of alpha -APM which precipitates therefrom.