| 发明名称 |
PEPTIDEBORONIC ACID, TRYPSIN LIKE PROTEASE INHIBITOR |
| 摘要 |
Peptides comprising C-terminal boronic acid derivatives of lysine, ornithine, and arginine, homoarginine and corresponding isothiouronium analogs thereof, of the formula <CHEM> are reversible inhibitors of trypsin-like serine proteases such as thrombin, plasma kallikrein and plasmin. |
| 申请公布号 |
JPS6463583(A) |
申请公布日期 |
1989.03.09 |
| 申请号 |
JP19880135770 |
申请日期 |
1988.06.03 |
| 申请人 |
E I DU PONT DE NEMOURS & CO |
发明人 |
CHIYAARUZU EIDORIAN KETONAA;ASHIYOKUKUMARU BIIKUKATSUPA SHIENBI |
| 分类号 |
C07K5/06;A61K;A61K38/00;A61K38/06;A61K38/55;A61P7/02;A61P29/00;C07F;C07F5/00;C07F5/02;C07K;C07K5/00;C07K5/04;C07K5/065;C07K5/08;C07K5/097;C07K5/10;C07K5/103;C07K14/81;C12N9/99 |
主分类号 |
C07K5/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
