发明名称 |
PREPARATION OF UNILAMELLAR LARGE DIAMETER LIPOSOMES, THEIR PHARMACEUTICAL APPLICATION IN VIEW OF THE ENCAPSULATION OF THE ACTIVE PRINCIPLE FOR SUSTAINED RELEASE, AND DEVICE THEREFOR |
摘要 |
PCT No. PCT/FR84/00221 Sec. 371 Date Jun. 6, 1985 Sec. 102(e) Date Jun. 6, 1985 PCT Filed Oct. 5, 1984 PCT Pub. No. WO85/01440 PCT Pub. Date Apr. 11, 1985.A device for obtaining unilamellar liposomes comprising means for forming a solution of lipids, a detergent (octylglucoside) and a pharmaceutically active substance; means for taking an aliquot quantity of said solution; permeable and/or semipermeable membrane partitions for eliminating said detergent by dialysis with polymers in the form of beads; and means for administering to patients the resulting solution free of detergent. |
申请公布号 |
DE3476338(D1) |
申请公布日期 |
1989.03.02 |
申请号 |
DE19843476338 |
申请日期 |
1984.10.05 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
PHILIPPOT, JEAN;LIAUTARD, JEAN-PIERRE |
分类号 |
A61K9/00;A61K9/127;A61K9/133;(IPC1-7):A61K9/50 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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