HYDROXYSTYRENE DERIVATIVES.

摘要

Hydroxystyrene derivatives of formula (I) and their salts are new: where R1 and R2 are Ph, benzyl or phenethyl, or R1 is OR5 and R2 is benzyl or PhSCH2-; R3 and R4 together are -CO-NH-CS-S- or a group of formula (II), (III) or (IV); R5 is H, 1-5C alkyl or benzyl; R6 is a group of formula (V), or pyridinyl, furyl or thienyl; X1 is H, halogen, Me, Et, OR7, nitro, aminosulphonyl or amino; m1 is 1 or 2; R7 is Me or Et; n1 is 0-3. Alternatively, when R1 and R2 are Ph, benzyl or phenethyl or R1 is OR5 and R2 is benzyl, then R3 may be CN and R4 may be carbamoyl, or R3/R4 together may be -CO-Y-CH2CH2- or -CO-NPh-NH-CO-(where Y is O or NH). Alternatively, R1 and R2 may be 1-3C alkyl and R3/R4 together may be (IV).