发明名称 |
Rebeccamycin derivative containing pharmaceutical composition |
摘要 |
There are disclosed analogs of the antitumor agent, rebaccamycin, which possess antineoplastic properties against mammalian, particularly experimental animal, tumor systems. The compounds of the invention are aminoalkylated derivatives of rebeccamycin produced by first reacting rebeccamycin with a strong base to obtain a reactive intermediate and then reacting the reactive intermediate with an aminoalkyl compound.
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申请公布号 |
US4808613(A) |
申请公布日期 |
1989.02.28 |
申请号 |
US19880169785 |
申请日期 |
1988.03.18 |
申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
KANEKO, TAKUSHI;WONG, HENRY S.;UTZIG, JACOB J. |
分类号 |
C07H19/044;(IPC1-7):A61K31/40 |
主分类号 |
C07H19/044 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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