发明名称 Phenanthrene derivatives
摘要 The present invention relates to compounds of formula (I) ArCH2R1 (I) or a monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30 carbon atoms in total); ethers, esters thereof; acid addition salts thereof; wherein Ar is a phenanthrene or substituted phenanthrene ring system; R1 contains not more than eight carbon atoms and is a group <IMAGE> wherein m is 0 or 1; R5 is hydrogen; R6 and R7 are the same or different and each is hydrogen or C1-3 alkyl optionally substituted by hydroxy; R8 and R9 are the same or different and each is hydrogen or C1-3 alkyl; <IMAGE> is a five-or six-membered saturated carbocyclic ring; R10 is hydrogen, methyl or hydroxymethyl; R11, R12 and R13 are the same or different and each is hydrogen or methyl; R14 is hydrogen, methyl, hydroxy, or hydroxymethyl.
申请公布号 US4808625(A) 申请公布日期 1989.02.28
申请号 US19870090578 申请日期 1987.08.28
申请人 BURROUGHS WELLCOME CO. 发明人 BAIR, KENNETH W.
分类号 C07C205/15;C07D263/52;C07D263/62;C07D263/64;C07D309/12;C07D319/06;C07D498/04;C07D521/00;(IPC1-7):A61K31/135;C07C93/00;C07C87/64 主分类号 C07C205/15
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