ACYL-PEPTIDE HYDROLASE AND METHODS OF PRODUCTION AND USE

摘要

The invention discloses the amino acid sequence of Acyl-Peptide Hydrolase. The invention relates to a DNA molecule encoded for APH, a vector incorporating the molecule, and the use of such vector to transform a host. The invention further relates to the expression by the host to produce APH, and the use of APH to catalyze the hydrolysis of an Nα-acetylated peptide or protein or the reaction between an Nα-acetyl amino acid donor and an acceptor protein with a free α-NH¿2? group.