摘要 |
<p>The present invention provides novel renin-inhibiting peptides of the formula X-A6-B7-C8-D9-E10-F11-G12-H13-I14-Z, containing aryl acid derived moieties of the formula XL2b which are substituted for Phe8-His9, X and Z are terminal groups, and the remaining variables are absent or are amino acid residues. Such inhibitors are useful for the diagnosis and control of renin-dependent hypertension and other related diseases.</p> |