发明名称 STABLE DRUG W/O EMULSION COMPOSITION
摘要 PURPOSE: To obtain a composition comprising a dispersing aqueous phase arbitrarily containing an electrolyte, a continuous oil phase containing a mineral oil and a volatile silicon solution, an organopolysiloxane, PPG-20 methyl glucose ether distearate and an active ingredient. CONSTITUTION: This composition comprises (A) a disperse aqueous phase arbitrarily containing a pharmaceutically permissible electrolyte (e.g. NaCl), (B) a continuous oil phase containing a mineral oil and a volatile silicon solution (e.g. octamethylcyclotetrasiloxane), (C) an organopolysiloxane emulsion of the formula [R is H or an alkyl; (n) is 10-200; (m) is 1-25; (o) is 1-100 when all (o)>(m); (p) is 7-17], (D) PPG-20 methyl glucose ether distearate and (E) an active medicine component (e.g. antiacne agent, ibuprofen or erythromycin). The composition is locally applicable to skin and exhibits marvelous skin permeating property.
申请公布号 JPS6445310(A) 申请公布日期 1989.02.17
申请号 JP19880092612 申请日期 1988.04.14
申请人 RICHARDSON VICKS INC 发明人 SUTEIIBUN ROBAATO BERU
分类号 A61K9/107;A61K8/06;A61K8/60;A61K8/891;A61K8/894;A61K9/10;A61K47/00;A61K47/34;A61Q19/00 主分类号 A61K9/107
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