GENUS-SPECIFIC LISTERIA ANTIGEN IDENTIFIED BY MONOCLONAL ANTIBODIES

摘要

Antigens characteristic of all species of Listeria except L. denitrificans comprising proteins found in Listeria heat extracts, the major antigen having a molecular weight of from about 30 to about 38 kD and comprising three immunogenically different epitopes and others comprising proteins having a molecular weight range of approximately 17 kD to the major antigen and comprising an epitope immunoreactive with antibodies that are also reactive with one of the three epitopes on the 30 to about 38 kD protein. The invention also comprises mouse monoclonal antibodies specifically reactive with the identified epitopes on these antigens.