发明名称 |
Novel pyrazinoxide compound of NF-1616-904 and a pharmaceutical composition containing the same and a process for its preparation. |
摘要 |
<p>A novel pyrazinoxide compound of NF-1616-904 having the formula (1), <CHEM> and a process for its preparation by hydrolyzing the intermediate compound of NF-1616-902 which is separated from a culture broth of a microorganism belonging to the genus Thielavia. The pyrazinoxide compound of NF-1616-904 possesses biological and pharmacological activities, and is a useful pharmaceutical for preventing and treating diseases caused by superoxide radicals (O2<-> ), and nephritis.</p> |
申请公布号 |
EP0303250(A2) |
申请公布日期 |
1989.02.15 |
申请号 |
EP19880112999 |
申请日期 |
1988.08.10 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
NAKANO, YOSHIMASA;SUGAWARA, MICHIHARU;UETSUKI, SETSUYOSHI;IZAWA, TAKETOSHI;KAWAGUCHI, TOMOYUKI;WADA, AKIRA |
分类号 |
A61K31/495;A61P1/16;A61P9/00;A61P9/08;A61P9/10;A61P13/02;A61P15/00;A61P37/06;A61P43/00;C07D403/06;C12P17/16;C12R1/645 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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