发明名称 Preparation for preventing or combating complications in diabetes.
摘要 <p>Preparation for preventing or combating complications in diabetes, characterized in that it comprises: (a) insulin or a salt or complex thereof, and (b) a peptide of the general formula I: H-L-Met(X)-L-Glu-L-His-L-Phe-D-Lys-L-Phe-Y or a salt or a N-acyl derivative thereof, wherein Met(X) represents the amino acid radical Met, Met(O) or Met(O2), Y represents the group Gly-Z or Z, and Z represents the hydroxyl group, an esterified hydroxyl group or a substituted or unsubstituted amino group. c</p>
申请公布号 EP0303308(A1) 申请公布日期 1989.02.15
申请号 EP19880201499 申请日期 1988.07.13
申请人 AKZO N.V. 发明人 HUISMAN, ROBBY
分类号 A61K38/28;A61K38/35;A61P3/08;A61P3/10;(IPC1-7):A61K37/26;A61K9/22 主分类号 A61K38/28
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