发明名称 Polycyclic hydrocarbon succinimides with psychotropic activity
摘要 There are disclosed compounds of the formula <IMAGE> <IMAGE> <IMAGE> +TR <IMAGE> <IMAGE> where X is methylene, ethylene or O and the dotted line represents an optional double bond, or one of Y or Z is <IMAGE> +TR <IMAGE> R1 is unsubstituted or substituted phenyl, 2-pyridinyl, 2-pyrimidinyl, 2-pyrazinyl or 3-pyridazinyl, where the substituents are selected from the group lower alkyl, lower alkoxy, halo, cyano, nitro, hydroxy and trifluoromethyl; m is 2-4; n is 1-3; o is 1-5; and the pharmaceutically acceptable salts thereof and their use as antipsychotic/anxiolytic agents having a low liability for extrapyramidal side effects.
申请公布号 US4804751(A) 申请公布日期 1989.02.14
申请号 US19870068470 申请日期 1987.06.30
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 ABOU-GHARBIA, MAGID A.
分类号 C07D209/58;C07D401/12;C07D403/12;(IPC1-7):A61K31/495;C07D401/06;C07D401/14 主分类号 C07D209/58
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