发明名称 FREMGANGSMAATE FOR FREMSTILLING AV 2-PENEMFORBINDELSER.
摘要 <p>Compounds of the general formula: <CHEM> in which R1, R2, R3, X and 2 are as defined herein, and their pharmaceutically acceptable salts; especially those subject to the following provisos: (i) when X is S, Z is O or =NR7 (R7 being as defined herein); (ii) when X is O, Z is O, S or =NR7; (iii) when X is -CH2-, Z is =NR7; (except that when R7 is H or C1-C6 alkyl and R2 is C1-C6 alkyl, then R1 cannot be acylamino; (iv) when X is (CH2)2, Z is=NR7; and their pharmaceutically acceptable salts. These compounds are antibacterial agents which can be incorporated into pharmaceutical compositions or used as intermediates in the preparation of such agents.</p>
申请公布号 NO159795(C) 申请公布日期 1989.02.08
申请号 NO19820000264 申请日期 1982.01.28
申请人 SCHERING CORPORATION 发明人 AFONSO, ADRIANO;HON, FRANK
分类号 C07D499/897;A61K31/397;A61K31/40;A61K31/415;A61P31/04;C07D205/08;C07D205/09;C07D463/00;C07D477/00;C07D477/04;C07D477/22;C07D487/04;C07D499/00;C07D499/04;C07D499/06;C07D499/32;C07D499/88;C07D503/00;C07F7/18;(IPC1-7):C07D499/00 主分类号 C07D499/897
代理机构 代理人
主权项
地址