发明名称 |
ANTIMICROBIAL AGENT FOR HUMAN OR ANIMAL |
摘要 |
PURPOSE:To obtain a low-toxic antimicrobial agent having excellent controlling activity against true fungi, by using FR109615 or its salts as active component. CONSTITUTION:The objective agent contains the compound FR109615 and its salt having controlling action against pathogenic microorganisms, especially pathogenic fungi (e.g. Candida albicans). The active component can be produced by culturing an FR109615-producing strain belonging to Streptomyces genus (e.g. Streptomyces setonii No.7562: FERM P-9444) in a nutrient medium under aerobic condition and separating from the cultured product. The culture is preferably carried out in a deep tank under aerobic condition for mass production. The FR109615 is (1R,2S)-2-aminocyclopentanecarboxylic acid of formula. |
申请公布号 |
JPS6438049(A) |
申请公布日期 |
1989.02.08 |
申请号 |
JP19880171686 |
申请日期 |
1988.07.08 |
申请人 |
FUJISAWA PHARMACEUT CO LTD |
发明人 |
MIYAUCHI MICHIYO;TSUJII EISAKU;EZAKI MASAMI;HASHIMOTO MASAHARU;OKUHARA MASAKUNI |
分类号 |
A01N37/44;A61K31/195;A61P31/04;C07C67/00;C07C227/00;C07C227/28;C07C229/48;C12P1/06;C12P13/00;C12R1/465 |
主分类号 |
A01N37/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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