摘要 |
An automatic chemistry machine particularly suitable for the automatic sequencing of DNA on the microliter scale including a source of reagents, a common means to transfer by contact microliter quantities of reagent, below 5 microliters, and a rotatable reaction surface to which said quantities of reagent are transferable, means to control the transfer means to access and contact specific spaced areas of the reaction surface, and means to control the rotation of the surface with regard to the transfer means action, the surface being formed to constrain flow of transferred reagent quantities over the surface and in a reaction area to mix under centrifugal action on faster rotation of the surface. |