发明名称 Cis-N-(2-aminocycloaliphatic)benzamide anti-convulsants
摘要 Certain cis-N-(2-amino-cycloalophatic)benzamides of the formula <IMAGE> (I) where m is 0, n is 2, r is alkyl, R1 and R2 are taken together with the nitrogen denote a pyrrolidine ring, X and Y are hydrogen or a halogen having an atomic number of from 9 to 35, e.g., cis-3,4-dichloro-N-methyl-n[2-(1-pyrrolidinyl)cyclohexyl]benzamide, and salts thereof, have been found to have CNS seizure blocking or preventing drug action, e.g., anti-convulsant drug properties with little or no analgesic properties.
申请公布号 US4801604(A) 申请公布日期 1989.01.31
申请号 US19870076411 申请日期 1987.07.21
申请人 THE UPJOHN COMPANY 发明人 VONVOIGTLANDER, PHILIP F.;SZMUSZKOVICZ, JACOB
分类号 A61K31/165;A61K31/40;C07D295/135;(IPC1-7):A61K31/40;C07D295/06 主分类号 A61K31/165
代理机构 代理人
主权项
地址