发明名称 2-alkenylene-thieno-1,2-thiazole derivatives with lipid-lowering activity
摘要 The invention relates to new thieno-1,2-thiazole derivatives of the formula <IMAGE> I wherein A, with the two carbon atoms of the thiazole ring, forms a group of the formula <IMAGE> IIa <IMAGE> IIb or <IMAGE> IIc and the broken line indicates the double bond present in the thieno structures of the formulae IIa and IIb, n denotes the integer 2, 3 or 4, R denotes hydrogen or lower alkyl, R1 denotes hydrogen, lower alkyl, halogen, trifluoromethyl, lower alkoxy or lower alkylthio and R2 denotes hydrogen, lower alkyl or halogen; and the pharmaceutically acceptable salts of compounds of the formula I wherein R denotes hydrogen, a process for their preparation, pharmaceutical products containing these compounds, and their use in medicaments. The compounds of the formula I and salts thereof have a lipid-lowering action.
申请公布号 US4801591(A) 申请公布日期 1989.01.31
申请号 US19860876673 申请日期 1986.06.19
申请人 CHEMIE-LINZ AKTIENGESELLSCHAET 发明人 BINDER, DIETER
分类号 A61K31/381;A61K31/425;A61K31/429;A61P3/06;A61P9/00;C07D513/04;(IPC1-7):C07D513/04 主分类号 A61K31/381
代理机构 代理人
主权项
地址