发明名称 |
Piperazinyl derivates of purines and isosteres thereof as hypoglycemic agents. |
摘要 |
<p>There are disclosed certain 6-piperazino-purine and heteroaromatic derivatives thereof which have oral hypoglycemic activity and with such ability to lower blood sugar are useful in the treatment of type II diabetes and/or obesity with associated insulin resistance. Processes for the preparation of such compounds and compositions containing such compounds as the active ingredient thereof are also disclosed.</p> |
申请公布号 |
EP0300726(A1) |
申请公布日期 |
1989.01.25 |
申请号 |
EP19880306584 |
申请日期 |
1988.07.19 |
申请人 |
MERCK & CO. INC. |
发明人 |
JOHNSTON, DAVID B. R.;TOLMAN, RICHARD L.;MAC COSS, MALCOLM;MARBURG, STEPHEN;MEURER, LAURA C. |
分类号 |
A61K31/495;A61K31/52;A61K31/522;A61P3/04;A61P3/08;A61P3/10;C07D471/04;C07D473/16;C07D473/18;C07D473/24;C07D473/32;C07D473/34;C07D473/40;C07D498/04;C07D513/04;C07F7/08;C07H19/16;(IPC1-7):C07D473/34;A61K31/44 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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