发明名称 Piperazinyl derivates of purines and isosteres thereof as hypoglycemic agents.
摘要 <p>There are disclosed certain 6-piperazino-purine and heteroaromatic derivatives thereof which have oral hypoglycemic activity and with such ability to lower blood sugar are useful in the treatment of type II diabetes and/or obesity with associated insulin resistance. Processes for the preparation of such compounds and compositions containing such compounds as the active ingredient thereof are also disclosed.</p>
申请公布号 EP0300726(A1) 申请公布日期 1989.01.25
申请号 EP19880306584 申请日期 1988.07.19
申请人 MERCK & CO. INC. 发明人 JOHNSTON, DAVID B. R.;TOLMAN, RICHARD L.;MAC COSS, MALCOLM;MARBURG, STEPHEN;MEURER, LAURA C.
分类号 A61K31/495;A61K31/52;A61K31/522;A61P3/04;A61P3/08;A61P3/10;C07D471/04;C07D473/16;C07D473/18;C07D473/24;C07D473/32;C07D473/34;C07D473/40;C07D498/04;C07D513/04;C07F7/08;C07H19/16;(IPC1-7):C07D473/34;A61K31/44 主分类号 A61K31/495
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