摘要 |
PURPOSE:To prepare coenzyme Q10 in high efficiency, by culturing a microbial strain belonging to Alcaligenes genus in a medium containing isopentenyl pyrophosphate and farnesyl pyrophosphate. CONSTITUTION:Alcaligenes sp.DK-605 (FERM-P No.6342) or Alcaligenes sp.DK- 515 (FERM-P No.6341) is inoculated in a nutrient medium containing 0.1-2mM of isopentenyl pyrophosphate and 0.05-1mM of farnesyl pyrophosphate per 1 liter of the medium, and cultured under aerobic condition at 5-8pH and 20- 40 deg.C. The objective coenzyme Q10 can be separated from the cultured bacterial cells. |