| 摘要 |
<p>Entitled : Triazolo¢ 4,3-b!pyridazines, process for their preparation and pharmaceutical compositions containing them. in the names of : Jacques BOURGUIGNON Jean-Pierre CHAMBON Camille Georges WERMUTH assigned to : SANOFI The invention relates to 1,2,4-triazolo ¢ 4,3-b!pyridazines substituted in the 7-position of formula : (I) in which R represents hydrogen, a lower alkyl group, a phenyl group, a chlorophenyl group or a benzyl group and R1 represents a phenyl, halogenophenyl, trifluoromethylphenyl, lower alkyl-phenyl or lower alkoxy-phenyl group or a phenyl-lower alkyl group, or one of its pharmaceutically acceptable salts. Said compounds antagonize the effects of benzodiazepines and therefore are useful as antidotes in the abuse of benzodiazepines and compounds acting on benzodiazepine receptors.</p> |
