发明名称 |
ANTIBODY COMPOSITIONS OF THERAPEUTIC AGENTS HAVING AN EXTENDED SERUM HALF-LIFE |
摘要 |
<p>A preferred complex of alpha-interferon with a monoclonal antibody complexes with the alpha-interferon without impairing its antiviral activity. The serum half-life of the interferon administered as the complex is substantially increased when compared to that of alpha-interferon administered alone.</p> |
申请公布号 |
CA1249222(A) |
申请公布日期 |
1989.01.24 |
申请号 |
CA19840462348 |
申请日期 |
1984.09.04 |
申请人 |
HYBRITECH INCORPORATED |
发明人 |
FRINCKE, JAMES M.;UNGER, BARBARA W.;BURNETT, KAREN G.;HERSH, EVAN M.;ROSENBLUM, MICHAEL G.;GUTTERMAN, JORDAN U. |
分类号 |
G01N33/531;A61K38/00;A61K38/21;A61K39/00;A61K39/395;A61K47/42;A61K47/48;C07K1/22;C07K14/005;C07K14/195;C07K14/52;C07K14/555;C07K14/56;C07K14/565;C07K14/57;C07K16/00;C07K16/24;C07K16/46;C07K19/00;C12N15/00;C12N15/02;C12P21/00;C12P21/08;G01N33/577;(IPC1-7):A61K39/395;A61K45/02 |
主分类号 |
G01N33/531 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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