PLEUROMUTILIN DERIVATIVES PROCESS FOR THEIR PREPARATION AND THEIR USE

摘要

PLEUROMUTILIN DERIVATIVES PROCESS FOR THEIR PREPARATION AND THEIR USE A compound of formula I I wherein R1 represents ethyl or vinyl and and R2 represents a five membered saturated heterocycle or amino alkyl unsubstituted or substituted in its alkyl moiety by hydroxy, in free form or in the form of an acid addition or quaternary salt, which compounds are indicated for use as chemotherapeutic agents e.g. as anti-bacterially active antibiotics and as veterinary agents e.g. in combatting microorganism infections and promoting growth in domestic animals.