摘要 |
<p>1-Substituted-spiro¢chroman-4,4'-imidazolidine!-2',5'-dione compounds are useful for treating antiarrhythmia and have the formula: (wherein: X1 and x2 are each hydrogen, halogen, alkyl, alkoxy, trifluoromethyl, trifuloroethoxy or nitro or together form alkylenedioxy; R1 and R2 are each hydrogen or alkyl or together form cycloalkyl; R3 and R4 are each hydrogen, alkyl, hydroxyalkyl or aralkyl or together with the nitrogen atom form saturated heterocyclic group; R5 and R6 are each hydrogen, phenyl or OR7 (R7 is hydrogen, acyl, alkyl or aralkyl) or together with the carbon atom form 4-or 5-membered cyclic group containing two oxygen atoms or R5 and R6 together form =O; and n is 2 to 7).</p> |