发明名称 HYDANTOIN DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND MEDICINE CONTAINING THE SAME
摘要 <p>1-Substituted-spiro¢chroman-4,4'-imidazolidine!-2',5'-dione compounds are useful for treating antiarrhythmia and have the formula: (wherein: X1 and x2 are each hydrogen, halogen, alkyl, alkoxy, trifluoromethyl, trifuloroethoxy or nitro or together form alkylenedioxy; R1 and R2 are each hydrogen or alkyl or together form cycloalkyl; R3 and R4 are each hydrogen, alkyl, hydroxyalkyl or aralkyl or together with the nitrogen atom form saturated heterocyclic group; R5 and R6 are each hydrogen, phenyl or OR7 (R7 is hydrogen, acyl, alkyl or aralkyl) or together with the carbon atom form 4-or 5-membered cyclic group containing two oxygen atoms or R5 and R6 together form =O; and n is 2 to 7).</p>
申请公布号 CA1249271(A) 申请公布日期 1989.01.24
申请号 CA19850472972 申请日期 1985.01.28
申请人 EISAI CO., LTD. 发明人 MINAMI, NORIO;MATHUKURA, MASAYUKI;UEDA, KOICHIRO;TANAKA, SATORU;IGARASHI, TOSHIJI
分类号 C07D491/06;A61K31/352;A61K31/415;A61K31/4188;A61K31/4245;A61K31/445;A61K31/495;A61K31/535;A61P9/04;A61P9/06;C07D233/78;C07D273/01;C07D407/02;C07D491/10;C07D491/107;C07D519/00;(IPC1-7):C07D491/107;A61K31/395;C07D491/20 主分类号 C07D491/06
代理机构 代理人
主权项
地址