摘要 |
<p>A compound of formula (I): <CHEM> or a pharmaceutically acceptable salt thereof, wherein: A<0> represents nitrogen or a moiety R<1>- @- wherein R<1> represents hydrogen, alkyl or a substituted or unsubstituted aryl group; R<2> represents a moiety R<3>-Y-Z- wherein R<3> represents substituted or unsubstituted phenyl, substituted or unsubstituted pyridyl or a substituted or unsubstituted oxazolyl group, and Y represents -(CH2)n- wherein n represents zero or any integer in the range of 1 to 6 and Z represents -CH2-,-CH(OH)- or -CO-; R<a> and R<b> each represent hydrogen or R<a> and R<b> together represent a bond; A represents a residue of a benzene ring, the carbon atoms of the residue having in total up to four substituents; and X represents O or S; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of the compound and composition in medicine.</p> |