发明名称 Thiazolidinedione derivatives.
摘要 <p>A compound of formula (I): &lt;CHEM&gt; or a pharmaceutically acceptable salt thereof, wherein: A&lt;0&gt; represents nitrogen or a moiety R&lt;1&gt;- @- wherein R&lt;1&gt; represents hydrogen, alkyl or a substituted or unsubstituted aryl group; R&lt;2&gt; represents a moiety R&lt;3&gt;-Y-Z- wherein R&lt;3&gt; represents substituted or unsubstituted phenyl, substituted or unsubstituted pyridyl or a substituted or unsubstituted oxazolyl group, and Y represents -(CH2)n- wherein n represents zero or any integer in the range of 1 to 6 and Z represents -CH2-,-CH(OH)- or -CO-; R&lt;a&gt; and R&lt;b&gt; each represent hydrogen or R&lt;a&gt; and R&lt;b&gt; together represent a bond; A represents a residue of a benzene ring, the carbon atoms of the residue having in total up to four substituents; and X represents O or S; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of the compound and composition in medicine.</p>
申请公布号 EP0299620(A1) 申请公布日期 1989.01.18
申请号 EP19880305285 申请日期 1988.06.09
申请人 BEECHAM GROUP PLC 发明人 HAIGH, DAVID BEECHAM PHARMACEUTICALS;HINDLEY, RICHARD MARK BEECHAM PHARMACEUTICALS
分类号 A61K31/425;A61K31/44;A61P3/06;A61P3/08;C07D417/06;C07D417/14;(IPC1-7):C07D417/06 主分类号 A61K31/425
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