发明名称 BRIDGED-DIAZABICYCLOALKYL QUINOLONE CARBOXYLIC ACIDS AND ESTERS
摘要 <p>Compounds of formula (I) and pharmaceutically acceptable acid addition salts thereof, wherein R1 is hydrogen, (C¿1?-C6) alkyl, or a pharmaceutically acceptable cation; R?2¿ is ethyl, fluoroethyl, p-fluorophenyl, p-hydroxyphenyl or cyclopropyl; R3 is fluorine or hydrogen; and R4 is (a) or (b), wherein n is 1 or 2 and R5 is hydrogen or (C¿1?-C3)alkyl are disclosed. Also disclosed are antibacterial pharmaceutical compositions comprising the foregoing compounds, methods of using the compounds in treating bacterial infections, and intermediates for the preparation of the compounds.</p>
申请公布号 WO1989000158(A1) 申请公布日期 1989.01.12
申请号 US1987001583 申请日期 1987.07.02
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