发明名称 |
METHODS OF PREPARING 11 BETA, 17 ALPHA, 20, 21-TETRA-HYDROXY STEROIDS AND CORRESPONDING 11 BETA, 17 ALPHA, 21-TRIHYDROXY-20-OXO STEROIDS |
摘要 |
A method for preparing 11 beta , 17 alpha , 20, 21-tetrahydroxy steroids of the pregnane class comprises incubating the corresponding 17 alpha , 20 alpha or beta , 21-trihydroxy steroid in the presence of a culture medium capable of effecting the 11 beta -hydroxylation which comprises a fungal culture of the genus Curvularia. A method for preparing 11 beta , 17 alpha , 21-trihydroxy-20-oxo steroids of the pregnane class comprises the hydroxylation method described above followed by conversion of the resulting 11 beta , 17 alpha , 20 alpha or beta , 21-tetrahydroxy steroid into the corresponding 11 beta , 17 alpha , 21-trihydroxy-20-oxo steroid. |
申请公布号 |
DE3566678(D1) |
申请公布日期 |
1989.01.12 |
申请号 |
DE19853566678 |
申请日期 |
1985.02.04 |
申请人 |
EASTMAN KODAK COMPANY |
发明人 |
GOODHUE, CHARLES THOMAS;KYDD, GWENDOLYN CLANTON;FOSTER, CHARLES HOWARD;MCCOMBS, CHARLES ALLAN |
分类号 |
C07J5/00;C12P33/08;C12R1/645;(IPC1-7):C12P33/08;C12P33/12 |
主分类号 |
C07J5/00 |
代理机构 |
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代理人 |
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主权项 |
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