发明名称 |
Bis-platinum complexes as chemotherapeutic agents |
摘要 |
A bis-platinum complex having the structure: <IMAGE> wherein X and Y are the same or different ligands and are halide, sulphate, phosphate, nitrate, carboxylate, substituted carboxylate or dicarboxylate. B and C are the same or different and are primary or secondary amines, or pyridine type nitrogens. A is a diamine or polyamine wherein the primary amine N atoms are coordinated to the Pt atom such that platinum is present as Pt2+. The complexes are useful in the inhibition of tumors.
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申请公布号 |
US4797393(A) |
申请公布日期 |
1989.01.10 |
申请号 |
US19860889397 |
申请日期 |
1986.07.25 |
申请人 |
UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE |
发明人 |
FARRELL, NICHOLAS;HACKER, MILES P.;MCCORMACK, JOHN J.;DEALMEIDA, SERGIO G. |
分类号 |
A61K33/00;A61K31/28;A61K33/24;A61P35/00;C07F15/00;(IPC1-7):C07F15/00 |
主分类号 |
A61K33/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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