发明名称 Bis-platinum complexes as chemotherapeutic agents
摘要 A bis-platinum complex having the structure: <IMAGE> wherein X and Y are the same or different ligands and are halide, sulphate, phosphate, nitrate, carboxylate, substituted carboxylate or dicarboxylate. B and C are the same or different and are primary or secondary amines, or pyridine type nitrogens. A is a diamine or polyamine wherein the primary amine N atoms are coordinated to the Pt atom such that platinum is present as Pt2+. The complexes are useful in the inhibition of tumors.
申请公布号 US4797393(A) 申请公布日期 1989.01.10
申请号 US19860889397 申请日期 1986.07.25
申请人 UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE 发明人 FARRELL, NICHOLAS;HACKER, MILES P.;MCCORMACK, JOHN J.;DEALMEIDA, SERGIO G.
分类号 A61K33/00;A61K31/28;A61K33/24;A61P35/00;C07F15/00;(IPC1-7):C07F15/00 主分类号 A61K33/00
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