发明名称 NOVEL LECTIN AND PRODUCTION THEREOF
摘要 NEW MATERIAL:Lectin TGA separated from a plant of Tulipa genus, having a molecular weight of 40,000 (measured by gel-filtration) and exhibiting agglutination activity to mouse erythrocyte but free from agglutination activity to sheep and human erythrocyte and microbial cell of Saccharomyces cerevisiae, Candida tropicalis, Escherichia coli, Staphylococcus aureus and Bacillus subtilis. USE:A biochemical reagent useful for the investigation of the structure and distribution of sugars on the cell surface and for the specific purification, etc., of composite sugar. Useful also as an immunoenhancer. PREPARATION:The objective substance can be produced by grinding a plant body (preferably bulb) of a plant belonging to Tulipa genus (e.g. Tulipa gesneriana) optionally in the presence of an aqueous solvent, removing solid components from the ground product and subjected the obtained liquid to separation and purification treatments comprising a combination of e.g. fractionation with ammonium sulfate, column chromatography, etc.
申请公布号 JPS646299(A) 申请公布日期 1989.01.10
申请号 JP19870160576 申请日期 1987.06.26
申请人 KINKI UNIV 发明人 ODA YASUO;MINAMI KAZUO;ICHIDA SEIJI;AONUMA SHIGERU
分类号 A61K38/36;A61K36/00;A61K36/896;A61P37/00;A61P37/04;C07K1/22;C07K14/415;C07K14/42 主分类号 A61K38/36
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