发明名称 |
Potentiating formulations |
摘要 |
A composition for testing or treating microbial systems or infections, comprising an effective potentiating amount of a microbial dihydropteridine antagonist, which itself inhibits hydroxymethyldihydropteridine pyrophospokinase and has a sufficiently low toxicity, in combination with an effective amount of a competitor of para-aminobenzoic acid or an inhibitor of dihydrofolate reductase or both, its method of preparation, and its use in the inhibition of the production of dihydrofolic acid by microorganisms under in vivo or in vitro conditions.
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申请公布号 |
US4795639(A) |
申请公布日期 |
1989.01.03 |
申请号 |
US19770778264 |
申请日期 |
1977.03.16 |
申请人 |
BURROUGHS WELLCOME CO. |
发明人 |
BURCHALL, JAMES J.;BUSHBY, STANLEY R. M.;CULLEN, ROBERT;DUNKLEY, MICHAEL J. W.;FERONE, ROBERT |
分类号 |
A61K31/635;C07D475/04;(IPC1-7):A61K31/505;A61K31/63;A61K31/625 |
主分类号 |
A61K31/635 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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