Optically active borinic esters and ketones

摘要

A process for synthesizing an optically pure ketone comprising the steps of: treating an appropriate optically pure boronic ester with an organolithium compound at -78 DEG C. to obtain the "ate" complex, separating the optically pure borinic ester from the complex and converting said borinic ester into an optically pure ketone represented by the formulae: R*COR1 and R*COC 3BOND CR1 wherein R* is a chiral organyl moeity and R1 is an achiral organyl moeity.