发明名称 |
FOERFARANDE FOER FRAMSTAELLNING AV 2-ARYLOXIPROPIONSYROR. |
摘要 |
A process is provided for the enrichment in R isomer of an aryloxypropionic acid ester and for the stereoselective hydrolysis of an aryloxypropionic acid ester to form the corresponding aryloxypropionic acid in predominantly S configuration which comprises subjecting an aryloxypropionic acid ester of formula I <CHEM> wherein A is an ester residue and preferably an alkyl group, optionally substituted or branched, wherein R min is an optionally substituted aryl or heterocyclic ring system, containing in addition to carbon atoms one or more atoms selected from nitrogen, sulphur and oxygen, this ring system being optionally substituted and wherein B and D are for example a hydrogen or a halogen atom, to the action of a microorganism or substance derived thereof capable of stereoselective hydrolysis of the COOA group to form the corresponding carboxylic acid predominantly is S configuration. |
申请公布号 |
FI883151(A) |
申请公布日期 |
1989.01.03 |
申请号 |
FI19880003151 |
申请日期 |
1988.07.01 |
申请人 |
GIST-BROCADES N.V.;SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. |
发明人 |
BERTOLA, MAURO ATTILIO;DE SMET, MARIE JOSE;MARX, ARTHUR FRIEDRICH;PHILLIPS, GARETH THOMAS |
分类号 |
C07C59/125;A01N37/36;C07C51/00;C07C67/00;C07D213/64;C07D521/00;C12N1/20;C12N9/18;C12P7/40;C12P17/00;C12P41/00;C12R1/01;C12R1/10;C12R1/125;C12R1/19;C12R1/445 |
主分类号 |
C07C59/125 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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