| 摘要 |
1. A process for the preparation of 2,4-diamino-5-(3,5-dimethoxy-4-(2-methoxyethoxy)-benzyl)- pyrimidine represented by formula I see diagramm : EP0065705,P4,F1 characterized in that beta-anilino-alpha-(3,5-dimethoxy-4-(2-methoxyethyl)- benzyl)-acrylonitril represented by formula II see diagramm : EP0065705,P4,F2 is brought to reaction with guanidine as a free base in a solution containing ethanol under reflux. |
