| 摘要 |
The invention relates to new triphenylmethyl derivatives of sn-glycero-3-phosphocholine and sn-glycero-3-phosphoethanolamine of the general formula <IMAGE> I in which T denotes a triphenylmethyl group which is unsubstituted or monosubstituted or polysubstituted by C1-C6-alkyl, C1-C6-alkoxy or halogen, and the radicals R1, R2 and R3 either are identical and each represent a methyl group, or are different, in which case two of the radicals R1, R2 and R3 always denote hydrogen, and the third radical represents a triphenylmethyl group which is unsubstituted or monosubstituted or polysubstituted by C1-C6-alkyl, C1-C6-alkoxy or halogen, a process for their preparation, and their use for the preparation of chemically defined pure enantiomeric 1,2-diacyl-sn-glycero-3-phosphocholines and 1,2-diacyl-sn-glycero-3-phosphoethanolamines which are substituted in positions 1 and 2 of the glycerol, independently of one another, by different acyl radicals. |
