发明名称 TRANSCRIPTION-BASED NUCLEIC ACID AMPLIFICATION/DETECTION SYSTEMS
摘要 The present invention is predicated on the novelty of certain RNA transcripts, their production, optional replication, and use, to achieve desired amplification and detection of corresponding (in sequence) target nucleic acid sequence. The transcripts correspond in sequence to a target nucleic acid sequence contained in an original sample amongst a mixture of nucleic acids, and therefore, the presence of the transcripts in amplified form provides for their detection, and hence by correspondence, the in vitro or x-vivo detection of the presence of the target nucleic acid sequence in said sample.
申请公布号 WO8810315(A1) 申请公布日期 1988.12.29
申请号 WO1988US02108 申请日期 1988.06.17
申请人 SISKA DIAGNOSTICS, INC. 发明人 GINGERAS, THOMAS, RAYMOND;MERTEN, ULRICH;KWOH, DEBORAH, YANTIS
分类号 C12N15/09;C12N15/00;C12N15/10;C12Q1/68;C12Q1/70 主分类号 C12N15/09
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