摘要 |
<p>Compounds having biological response modifying activity and their methods of production are described. The compounds have the formula: <CHEM> wherein each X is (CH2)n wherein 1 </= n </= 3; <CHEM> where R<4> is lower alkyl; CH2S; or CH2O; and R<3> and R<5>, independently, are H, fluoro, nitro, amino, alkylamino, dialkylamino, arylamino, acylamido, carboxy, azido, lower alkoxy, trimethylsulphonyl, trifluoromethanesulphonyl, or lower alkoxycarbonyl, provided that when X is (CH2)2, R<3> cannot be H; or a pharmaceutically acceptable salt thereof.</p> |