发明名称 |
AQUEOUS STEROID FORMULATIONS FOR NASAL ADMINISTRATION |
摘要 |
A non-stinging aqueous anti-inflammatory steroid formulation suitable for intranasal administration comprises: an anti-inflammatory steroid in an amount between about 0.01% and about 0.05% (w/v); propylene glycol in an amount between about 2% and about 10% (w/v); PEG 400 in an amount between about 10% and about 25% (w/v); polysorbate 20 in an amount between about 1% and about 4% (w/v); an effective amount of a preservative; an effective amount of a stabilizer; an effective amount of an antioxidant; water; and pH buffering agent sufficient to adjust the pH of the resulting solution to between about 3.5 and about 7. |
申请公布号 |
ZA8703663(B) |
申请公布日期 |
1988.12.28 |
申请号 |
ZA19870003663 |
申请日期 |
1987.05.21 |
申请人 |
SYNTEX (U.S.A.) INC. |
发明人 |
ERIC JOEL BENJAMIN;SHABBIR TYABJI ANIK;YA-YUN TRACY LIN |
分类号 |
A61K9/00;A61K9/08;A61K9/10;A61K31/57;A61K31/58;A61K47/10;A61K47/32;A61K47/34;A61P27/16;A61P29/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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