发明名称 ANTIVIRAL AGENT
摘要 PURPOSE:To obtain an antiviral agent, especially antiretroviral agent, especially preferably anti-AIDS virus agent containing polysaccharides or protein polysaccharide collected from sea weeds, especially Chlorophyceae as an active ingredient. CONSTITUTION:A sea weed of Chlorophyceae belonging to the genera Chlorella, Ulva, Hydrodictyon, Codium, Acetabularia, etc., is extracted with an aqueous solvent to afford a polysaccharide or protein polysaccharide, which is used as an active ingredient and formulated according to a conventional method to provide the aimed product. The resultant agent is administered orally in dose of 0.1-1,000mg, preferably 1-100mg/kg 1-3 times daily. Properties of the above-mentioned polysaccharide or protein polysaccharide are as follows: positive or slightly positive to alpha-naphthol sulfuric acid reaction, indole sulfuric acid reaction, phenol sulfuric acid reaction, etc.; elemental analysis, containing C 20-55%, H 3-9%, N <16% as main ingredient; pH, 6.0-7.5; soluble in water based solvent, insoluble in organic solvent; appearance, white, green or brawn; molecular weight, 10<3>-3X10<6>.
申请公布号 JPS63316733(A) 申请公布日期 1988.12.26
申请号 JP19870152088 申请日期 1987.06.18
申请人 KUREHA CHEM IND CO LTD 发明人 OHARA MINORU;OGUCHI YOSHIHARU;MATSUNAGA KENICHI;HIROSE KUNITAKA;KADOCHI JIYUNJI;SUGITA NORIFUMI;FURUSHO TAKAO;MUTO SHIGEAKI;NIIMURA KOICHI;YOSHIKUMI CHIKAO;TAKAHASHI MASAAKI
分类号 A61K36/02;A61K31/715;A61K36/05;A61K38/00;A61P31/12 主分类号 A61K36/02
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