| 摘要 |
The invention relates to a method and means for detecting microbial pathogens in a sample body fluid which is suspected to contain antimicrobial factors by incorporating in the sample fluid an effective amount of an antimicrobial factor deactivating system which is noncidal to the microbial pathogens. The antimicrobial deactivating system includes aminoglycoside blocking agents, such as sodium polyanetholsulfonate and sodium amylosulfate; penicillin and cephalosporin deactivating agents, such as thioglycolate, glutathione, N-acetyl-cysteine and cysteine; a sulfa compound deactivating agent, such as p-aminobenzoic acid and enzymes which are specific to antibiotics. The antimicrobial factor deactivating system may also contain other compounds depending on the usage of the systems, for example lysing agents and anticoagulants. |
