发明名称 PLATINA-DIAMIN-KOMPLEX, ETT FORFARANDE FOR FRAMSTELLNING DERAV, ETT FORFARANDE FOR FRAMSTELLNING AV EN MEDICINSK KOMPOSITION UNDER ANVENDNING AV ETT DYLIKT PLATINA-DIAMIN-KOMPLEX FOR BEHANDLING AV CANCER SAMT DEN PA DET
摘要 This invention relates to novel platinum compounds, a method for the preparation thereof, a pharmaceutical composition using the novel compounds and a method for the treatment of cancer using the pharmaceutical composition, wherein the platinum-(II)-diamine complexes are characterized by the formula <IMAGE> wherein R1 and R2 are both ethyl or together with the carbon atom, to which they are bonded, a cyclohexyl group, R3 and R4 are both a hydrogen atom and X is a malonate group, an ethylmalonate group, a hydroxymalonate group, a carboxyphthalate group, a bischloro acetate group, a cyclobutane-1,1-dicarboxylate group, a dinitrate group or an oxalate group or a sodium salt of these groups.
申请公布号 SE8305783(L) 申请公布日期 1984.04.22
申请号 SE19830005783 申请日期 1983.10.20
申请人 TNO 发明人 VERBEEK F;BERG J;BULTEN E J
分类号 A61K31/28;A61K31/282;A61P35/00;C07C211/65;C07F15/00;(IPC1-7):C07F15/00;A61K31/55 主分类号 A61K31/28
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