摘要 |
<p>Tetrapeptide compounds of general formula: <IMAGE> I in which R denotes: a hydrogen atom, a straight- or branched-chain alkyl radical containing from 1 to 4 carbon atoms, an aryl radical such as phenyl or a heterocyclic aromatic radical such as thienyl, optionally substituted with a hydroxy, amino, mercapto, methylthio or lower alkyl group, a lower aralkyl radical such as benzyl, R' denotes a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 4 carbon atoms, X denotes an oxygen atom or an NH group, Y denotes an oxygen or sulfur atom when X denotes an NH group, or Y denotes an NH group when X denotes an oxygen atom, t denotes 0 or 1, <IMAGE> denotes a nitrogen-containing polycyclic structure, their enantiomers, epimers and diastereoisomers, as well as their addition salts with a pharmaceutically acceptable acid or base. Medicinal products.</p> |