| 摘要 |
<p>Compounds of the formula (I): <CHEM> wherein X is H, F, Cl, Br, I, C1-4alkyl, CN, NO2, SO2NH2, COOH, OH, CHO, C1-4alkoxy, CH2OH, CH2OC1-4alkyl, CF3, C2F5, C3F7, SO2CH3, SO2CF3, or CO2CaH2a+1 wherein a is 1-5, or any accessible combination thereof of up to 5 substituents; R and R min independently are H or C1-4alkyl; and n is 1-5; or any pharmaceutically acceptable salt or hydrate thereof, processes for their preparation; intermediates used in their preparation; compositions containing them and their use in therapy as dopamine- beta -hydroxylase inhibitors.</p> |
