| 发明名称 |
Novel proteins with factor VIII activity, process for their preparation using genetically engineered cells and pharmaceutical compositions containing them. |
| 摘要 |
<p>Novel polypeptides having Factor VIII activity are provided as well as compositions and methods for their preparation. The polypeptides comprise derivatives and fragments of Factor VIII and have sequences substantially similar to portions of naturally occuring Factor VIII. The polypeptides find use in treatment of Hemophilia A.</p> |
| 申请公布号 |
EP0294910(A1) |
申请公布日期 |
1988.12.14 |
| 申请号 |
EP19880201209 |
申请日期 |
1988.06.13 |
| 申请人 |
GIST-BROCADES N.V. |
发明人 |
VAN OOYEN, ALBERT JOHANNES JOSEPH;PANNEKOEK, HANS C/O CENTRAAL LABORATORIES VAN DE;VERBEET, MARTINUS PHILIPPUS CENTRAAL LABORATORIES;VAN LEEN, ROBERT WILLEM |
| 分类号 |
A61K38/00;C07K14/755;C07K16/36;C12N15/12;C12N15/85 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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