PROCESS FOR THE MANUFACTURE OF PHARMACEUTICAL COMPOSITIONS CONTAINING UNILAMELLAR LIPOSOMES

摘要

Process for the manufacture of pharmaceutical compositions containing unilamellar liposomes The present invention relates to a process for the maunfacture of pharmaceutical compositions in the form of aqueous dispersions containing unilammellar liposomes comprising (I) an amphiphatic compound having biological activity and (II) a phospholipid or an analogous lipid and, optionally, an additional lipid. The liposome dispersion is obtained by preparing a homogenous mixture of the components and by dispersing the homogenous mixture in an aqueous phase. The unilamellar liposomes can be used therapeutically as carriers of amphiphatic pharmaceuticals of extremely varied kinds.