Monoclonal antibody and method for preparation of hybridoma producing said antibody.

摘要

Disclosed are a monoclonal antibody which recognizes specifically an O-acylsialic acid containing sugar chain and a method for preparing a hybridoma capable of producing the monoclonal antibody, which comprises using an autoimmune disease animal as the immunization animal and/or using a substance containing said sugar chain adsorbed on Salmonella Minesota bacteria as the immunogen. The monoclonal antibody of the present invention capable of recognizing the above described sugar chain which may be considerd to be antigens related with human cancer are very useful in diagnosis of cancer.