| 发明名称 |
Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase. |
| 摘要 |
<p>The compounds of the present invention comprise substituted phenolic thioethers, sulfoxides, and disulfides that are specific inhibitors of 5-lipoxygenase and which, therefore, are useful in the treatment of local and systemic inflammation, allergy and hypersensitivity reactions and other disorders in which agents formed in the 5-lipoxygenase metabolic pathway are involved.</p> |
| 申请公布号 |
EP0293900(A2) |
申请公布日期 |
1988.12.07 |
| 申请号 |
EP19880108874 |
申请日期 |
1988.06.03 |
| 申请人 |
G.D. SEARLE & CO. |
发明人 |
MUELLER, RICHARD AUGUST;PARTIS, RICHARD ALLEN |
| 分类号 |
C12N9/99;A61K31/19;A61K31/215;A61K31/22;A61K31/34;A61K31/365;A61K31/366;A61P11/00;A61P29/00;A61P37/08;A61P43/00;C07D309/30 |
主分类号 |
C12N9/99 |
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代理人 |
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