发明名称 |
ANALOGIFREMGANGSMAATE FOR FREMSTILLING AV FARMAKOLOGISK AKTIVE BENZOAZEPINDERIVATER. |
摘要 |
Compounds of general formula I <IMAGE> (wherein A represents a <IMAGE> group, wherein R7 represents a C1-3 alkyl group, and B represents a methylene or carbonyl group or A represents a -CO-CO- group and B represents a methylene group; E represents an optionally substituted ethylene, n-propylene or n-butylene group; G represents an optionally substituted methylene or ethylene group; R1 and R2 represent a hydroxy, alkyl, alkoxy or phenyl-alkoxy group or one of them represents a hydrogen atom or together they represent an alkylenedioxy group; R3 and R4 represent hydrogen atoms, halogen atoms, trifluoromethyl, hydroxy, alkyl, alkoxy or cyano groups or one of them represents a nitro group or together they represent an alkylenedioxy group; R5 represents a hydrogen atom, an alkyl, hydroxy, alkoxy or optionally substituted amino group; and R6 represents a hydrogen atom, an alkyl, alkenyl, phenylalkyl or acyl group) and acid addition salts thereof show heart-rate reducing activity. <IMAGE> |
申请公布号 |
NO159166(C) |
申请公布日期 |
1988.12.07 |
申请号 |
NO19820001645 |
申请日期 |
1982.05.18 |
申请人 |
THOMAE GMBH, DR. KARL |
发明人 |
REIFFEN, MANFRED;HEIDER, JOACHIM;HAUEL, NORBERT;AUSTEL, VOLKHARD;EBERLEIN, WOLFGANG;KOBINGER, WALTER;PIEPER, HELMUT;KRUEGER, GERD;KECK, JOHANNES;LILLIE, CHRISTIAN;NOLL, KLAUS |
分类号 |
C07D223/18;A61K31/55;A61P9/06;A61P9/10;C07C59/64;C07D205/04;C07D223/16;C07D233/16;C07D243/00;C07D243/02;C07D243/04;C07D405/12;C07D491/04;C07D491/056 |
主分类号 |
C07D223/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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