FURYLMETHYL THIOETHYLAMIDE DERIVATIVE

摘要

NEW MATERIAL:The compound of formula I [R is group of formula II-VI; n is 0 or 1; m is 1, 2 or 3; X is O or S; p is 0, 1 or 2). EXAMPLE:N-{2-(3-furylmethylsulfonyl)ethyl}-4-{3-(piperidinomethyl)phen oxy}bu tylamide. USE:An anti-peptic ulcer agent having gastric mucosa protecting action in addition to the strong action to suppress the secretion of gastric acid based on excellent histamine H2 receptor antagonistic action. PREPARATION:The compound of formula I can be produced by reacting a compound of formula R-(CH2)n-X-(CH2)m-COOH with a compound of formula VII.